Blood vessel-lymphatic vessel separation and platelets
نویسندگان
چکیده
منابع مشابه
Regulation of lymphatic-blood vessel separation by endothelial Rac1.
Sprouting angiogenesis and lymphatic-blood vessel segregation both involve the migration of endothelial cells, but the precise migratory molecules that govern the decision of blood vascular endothelial cells to segregate into lymphatic vasculature are unknown. Here, we deleted endothelial Rac1 in mice (Tie1-Cre(+);Rac1(fl/fl)) and revealed, unexpectedly, that whereas blood vessel morphology app...
متن کاملRegulation of blood vessel versus lymphatic vessel growth in the cornea.
PURPOSE In the present study, the authors developed novel models to stimulate blood vessel formation (hemangiogenesis) versus lymphatic vessel formation (lymphangiogenesis) in the cornea. METHODS Micropellets loaded with high-dose (80 ng) or low-dose (12.5 ng) basic fibroblast growth factor (bFGF) were placed in BALB/c corneas. Angiogenic responses were analyzed by immunohistochemistry to qua...
متن کاملLymphatic vessel contractile activity and intestinal inflammation.
Edema is a consistent observation in inflammatory bowel disease (IBD), and immune responses are inevitable in inflammation. Because the lymphatic system is an integral part of both tissue fluid homeostasis and immune reactions, it is likely that lymphatics play a role in the complex etiology of IBD. Despite the consistent findings that the lymphatic system is altered during gastrointestinal inf...
متن کامل[The prognostic significance of lymphatic vessel and blood vessel invasion in peripherally located adenocarcinoma of the lung].
要 旨:末 梢 型 肺 腺 癌 の 脈 管 侵 襲 と予 後 と の 関 連 を検 討 し た.1989年1月 か ら1999年12月 ま で に 切 除 し た 末 梢 型 肺 腺 癌344例 全 例 を対 象 と した.平 均 観 察 期 間 は42カ 月,5生 率 は68.2%で あ っ た.脈 管 侵 襲 別 の5生 率 は, ly0v0群96%, ly0v1群75%,ly1v0群75%, ly1v1群65%, ly2, 3 and/or v2, 3(以 下lyv2-3)群37%で, ly0v0 群 の 予 後 は 明 らか に 良 好 で あ っ た.ly0v0症 例 の97%はI期 症 例 で,ly0v0症 例 はIA期 症 例 の51%, IB期 症 例 の23%を 占 め た が,IIA期 以 上 の 症 例 に は わ ず か で あ っ た.IA期 症 例 の 脈...
متن کاملTargeting lymphatic vessel functions through tyrosine kinases
The lymphatic vascular system is actively involved in tissue fluid homeostasis, immune surveillance and fatty acid transport. Pathological conditions can arise from injury to the lymphatics, or they can be recruited in the context of cancer to facilitate metastasis. Protein tyrosine kinases are central players in signal transduction networks and regulation of cell behavior. In the lymphatic end...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis
سال: 2011
ISSN: 1880-8808,0915-7441
DOI: 10.2491/jjsth.22.81